Creative Proteomics can provide untargeted lipidomic analysis service for hundreds of lipids, providing technical support for research in agricultural science, biomarkers, cardiovascular disease, obesity, new drug development, and other aspects.
Lipids are a class of hydrophobic or amphiphilic molecules that play an important role in cell development, energy storage, signal transduction, material transport, and other life activities. The lipidome consists of 8 major classes, 300 subclasses, and thousands of lipids of varying. Untargeted lipidomic analysis can analyze multiple lipids simultaneously, allowing researchers to study physiological and pathological changes in organisms through differences in lipid profiles.
Service Content of Untargeted Lipidomics Analysis
Creative Proteomics has established an advanced mass spectrometry technology platform. Gas chromatography, atmospheric pressure ionization (API), and matrix-assisted laser desorption ionization (MALDI) combined with mass spectrometry are widely used in lipidomics analysis services. We first perform processing such as sample separation before MS analysis. Then select the most suitable technology to measure the mass-to-charge ratio (m/z) of ionic substances according to the needs of customers. MS can provide molecular weight information, while tandem mass spectrometry (MS/MS) or multistage fragmentation (MSn) can provide structural information. Finally, we combined the mass-to-charge ratio of the sample and the bioanalysis software to analyze the lipids in the sample.
Mass Spectrometry Facilities and Projects
AB Sciex API 4000 Mass Spectrometer Coupled with a Shimadzu LC-20AD HPLC System
AB Sciex 4000Qtrap Mass Spectrometer Coupled with a Shimadzu LC-20AD HPLC System
AB Sciex 6500QTRAP Mass Spectrometer Coupled with a Shimadzu LC-20AD HPLC System
Thermo Orbitrap Exploris-120 Mass Spectrometer Coupled with a Shimadzu LC-20AD HPLC System
Requirements for Samples
- We accept many types of samples, including animal, plant solid tissues, microorganisms (bacteria/fungi), liquids (root exudates, etc.).
- Please consult the staff for specific requirements of samples.
Deliverables
- Experimental steps
- Relevant mass spectrometry parameters
- Details of the identified phosphorylation sites
- Mass spectrometry images
- Raw data
Applications of Untargeted Lipidomics Analysis
- Biomarkers
- Precision medicine
- Stress mechanisms
- Plant metabolism
- Growth and development mechanisms, etc.
Advantages of Untargeted Lipidomics Analysis
- Extensive database containing profiles of a wide range of lipid molecules.
- Advanced and high-resolution mass spectrometry technology platform.
- Professional technical team with a strict quality control system.
Service Process
Creative Proteomics has built a comprehensive mass spectrometry technology platform to provide quality services in the new field of lipidomics research. If you are interested in our untargeted lipidomics analysis service, please contact us today for technical support.
The service is for research only, not for clinical use.
