Measurement of Metabolites Molecular Weight

Creative Proteomics is engaged in the metabolomics-related business, and has long been engaged in metabolite physical and chemical property analysis, structure prediction, and other related services, and provides customers with efficient measurement service of metabolites molecular weight.

Molecular weight (MW) is one of the most important properties of macromolecules. The molecular weight of a metabolite is a fundamental physicochemical property parameter for the study of metabolite characteristics and is the sum of the relative atomic masses in each structure of the metabolite. The correctness of molecular weight affects the accuracy of subsequent structure determination of metabolites. The measurement of molecular weight of metabolites can be done in various ways and is usually done using mass spectrometry facilities. Mass spectrometry has many advantages for determining the molecular weight of metabolites, such as less sample loss, higher sensitivity, higher resolution, and higher accuracy.

Service Content of Measurement of Metabolites Molecular Weight

Creative Proteomics determines molecular mass by measuring ionic charge-to-mass ratio (charge-to-mass ratio) analysis. Our service is not only for unmodified synthetic biomolecules but also for the determination of modified synthetic and natural biomolecules. A pre-treated sample is placed in an ion source, which ionizes it, generating positively charged ions with different charge-to-mass ratios, which are then accelerated by an electric field to form an ion beam, which enters the mass analyzer. In the mass analyzer, the electric and magnetic fields are used to disperse the ions at opposite velocities and focus them separately to obtain a mass spectrum to determine their mass.

Mass Spectrometry Facilities and Projects

• Bruker timsTOF Pro Mass Spectrometer
• Thermo Scientific™ UHPLC-Q Exactive Orbitrap Mass Spectrometer
• Thermo Scientific™ Orbitrap Fusion™ Tribrid™ Mass Spectrometer

Requirements for Samples

• We accept almost all samples. Please contact us for specific requirements.
• Please reduce or completely remove salt adducts from sample species.
• Please provide the specific concentration, volume, preparation time, and source for each sample. Please also provide information about the samples and the control and experimental samples (if there are subgroups, describe in detail the subgroup analysis information.).

Deliverables

• Experimental steps
• Relevant mass spectrometry parameters
• Details of the identified phosphorylation sites
• Mass spectrometry images
• Raw data

Advantages of Measurement of Metabolites Molecular Weight

• Fast experimental cycle.
• Accurate and error-free experimental data.
• Customized molecular weight determination services are available.

Service Process

Creative Proteomics has a long history of providing measurement service of metabolites molecular weight to researchers and teams. We guarantee to provide high resolution assays and high-accuracy data to quickly solve your project needs. If you are interested in our measurement service, please contact us today.