Creative Proteomics has long been engaged in metabolomics analysis services, with rich experimental experience and advanced mass spectrometry facilities. We can provide professional metabolomics analysis service for a variety of biological samples.
The phenotype, structure, and physiological activities of organisms are determined by the co-regulation of DNA, RNA, proteins, and metabolites. However, genes and life activities are often not directly related, and it is challenging to study the structure and regulatory genes that control key pathways. Metabolomics analysis mainly studies the characteristics of the metabolic network and the characteristics of metabolite changes involved. We use mass spectrometry facilities to detect all small molecule metabolites and use bioinformatics methods to explore and reveal the overall metabolic characteristics or physiological activity rules of living organisms.
Service Content of Metabolomics Analysis of Biological Specimens
For this service, there is no doubt that Creative Proteomics provides sample processing services and processes different biological samples to extract metabolites. Then use our gas chromatography-mass spectrometry (GC-MS), and liquid chromatography-mass spectrometry (LC-MS), two technology platforms to complete the qualitative and quantitative analysis of metabolites. For the analysis of metabolites such as water-soluble metabolites, some lipids, and organic acid metabolites, we typically use GC-MS. For the analysis of metabolites such as amino acids, sugars, alcohols, organic acids, amines, etc., we usually use LC-MS. At the same time, we provide a series of analytical services including but not limited to single/multi-dimensional statistical analysis, correlation analysis, heat map analysis, and metabolic pathway analysis.
Mass Spectrometry Facilities and Projects
- Thermo Scientific™ UHPLC-Q Exactive Orbitrap Mass Spectrometer
- Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
- Thermo Scientific™ Q Exactive™ HF Hybrid Quadrupole-Orbitrap Mass Spectrometer
Requirements for Samples
- In addition to easy-to-handle samples such as blood and serum, samples from cells, tissues, organs, or bacteria can be subjected to metabolomics analysis.
- To ensure the reliability of the experimental results, please provide as many replicate samples as possible.
- Please provide the specific concentration, volume, preparation time, and source of each sample. And inform the sample information as well as the control and experimental samples (if there is a group, describe the group information in detail.)
Deliverables
- Experimental steps
- Relevant mass spectrometry parameters
- Details of the identified phosphorylation sites
- Mass spectrometry images
- Raw data
Applications of Metabolomics Analysis of Biological Specimens
- For research on drug mechanisms and other aspects.
- Effectively advance your research in disease mechanisms.
- Accelerate your research progress in tissue development regulatory mechanisms.
Service Process
Creative Proteomics is an expert in the metabolomics analysis of biological samples. We can provide optimal experimental plans to quickly assist in promoting your research projects. Please contact us today for a quote if you are interested in our metabolomics analysis service for biological samples.
The service is for research only, not for clinical use.
